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| Compliance and the
Quality of Life of your
Patients |
Extraordinary service, training and round-the-clock assistance are
important benefits that your patient receives when purchasing an AdvantaJet®
needle-free jet injection system.
Independent Studies show that Jet
injection increases insulin absorption over needle and syringes methods.
Glucose homeostasis in individuals with a healthy pancreas is maintained
by the rapid release of insulin in response to nutrient intake. Insulin
concentrations increase several fold and reach peak levels 60 to 90 minutes
after ingestion of a mixed meal. People with diabetes who inject regular insulin
( rapid acting) subcutaneously with a needle and syringe experience a much
slower absorption rate, frequently resulting in post-meal hyperglycemia. These
same subcutaneous injections can also lead to excessively high insulin levels
several hours after the meal, resulting in hypoglycemia.
In controlled
studies, three independent laboratories have demonstrated that insulin is
absorbed more rapidly into the circulation when administered by jet injection,
as compared to conventional needle and syringe injections. As a consequence,
postmeal insulin profiles achieved are closer to those seen in individuals with
a normally functioning pancreas. In short-term studies, this characteristic of
jet injection can be shown to result in improved glycemic responses to meals. In
a recent long-term study, investigators have shown equal improvement in diabetes
control as assessed by glycolsylated hemoglobin after three months of treatment
with insulin pump therapy as compared to multiple daily injections administered
by jet injection.
The AdvantaJet® needle-free injection systems assist you
with compliance and improves quality of life for your patients.
With the
results of the Diabetes Complication and Control Trials (DCCT) documenting
reduced complications with increased injection regimens, compliance becomes
increasingly important. Since insulin administration by jet injector has been
reported to be less painful than needle injections, one would anticipate better
compliance with multiple daily injection regimens when jet injection is used.
However, controlled studies have yet to be performed.
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